Wednesday, November 01, 2006

Pyloric Stenosis

Jack underwent surgery yesterday to correct his pyloric stenosis. Taylor and I (and Jack) are very tired and are trying to recouperate right now, but I wanted to provide some info. Jack is doing fantastically well and should be home tomorrow. Thank you to everyone who called and visited and for everyone else who sent their prayers. You will never know how much that all meant to us. Thank you. Below is some info on what Jack has gone through.

The following information is taken from Kidshealth.org

What Is Pyloric Stenosis?

Pyloric stenosis is a narrowing of the pylorus, the lower part of the stomach through which food and other stomach contents pass to enter the small intestine. When an infant has pyloric stenosis, the muscles in the pylorus have become enlarged to the point where food is prevented from emptying out of the stomach.

Also called infantile hypertrophic pyloric stenosis or gastric outlet obstruction, pyloric stenosis is fairly common - it affects about three out of 1,000 babies in the United States. Pyloric stenosis is about four times more likely to occur in firstborn male infants. It has also been shown to run in families - if a parent had pyloric stenosis, then an infant has up to a 20% risk of developing the condition. Pyloric stenosis occurs more commonly in Caucasian infants than in babies of other ethnic backgrounds, and affected infants are more likely to have blood type B or O.

Most infants who develop pyloric stenosis are usually between 2 weeks and 2 months of age - symptoms usually appear during or after the third week of life. It is one of the more common causes of intestinal obstruction during infancy that requires surgery.
What Causes Pyloric Stenosis?

It is believed that babies who develop the condition are not born with pyloric stenosis, but that the progressive thickening of the pylorus occurs after birth. An affected infant begins showing symptoms when the pylorus is so thickened that the stomach can no longer empty properly.

It is not known exactly what causes the thickening of the muscles of the pylorus - it may be a combination of several factors. Some researchers believe that maternal hormones could be a contributing cause. Others believe that the thickening of the muscle is the stomach's response to some type of allergic reaction in the body.

Some scientists believe that babies with pyloric stenosis lack receptors in the pyloric muscle that detect nitric oxide, a chemical in the body that tells the pylorus muscle to relax. As a result, the muscle is in a state of contraction almost continually, which causes it to become larger and thicker over time. It may take some time for this thickening to occur, which is why pyloric stenosis usually appears in babies a few weeks after birth.

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